Undriven Bead Diffusion Through Extracellular Matrix
نویسندگان
چکیده
منابع مشابه
Cell Migration through Extracellular Matrix
Every so often, a paper comes along that brings clarity to an issue. Clarity is not necessarily a final resolution, but rather a conceptual framework for productively addressing that issue. Such a paper could be based on a breakthrough discovery, an intriguing observation, a flash of intuition , or a systematic analysis. An excellent example of the latter is in this issue of The Journal of Cell...
متن کاملEngineering extracellular matrix through nanotechnology.
The goal of tissue engineering is the creation of a living device that can restore, maintain or improve tissue function. Behind this goal is a new idea that has emerged from twentieth century medicine, science and engineering. It is preceded by centuries of human repair and replacement with non-living materials adapted to restore function and cosmetic appearance to patients whose tissues have b...
متن کاملChanges in diffusion through the brain extracellular space.
ECS (extracellular space) works as the microenvironment of brain cells. Diffusion through ECS may be described through an effective diffusion coefficient, D (e), which in turn depends on ECS porosity, epsilon, and tortuosity, T. In the present research, diffusion data together with epsilon and T were collected from the specialized literature and analysed to seek a correlation of T versus epsilo...
متن کاملExtracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation
Mesenchymal stem cell (MSC) differentiation is regulated by the extracellular matrix (ECM) through activation of intracellular signaling mediators. The stiffness of the ECM was shown to be an important regulatory factor for MSC differentiation, and transcriptional coactivator with PDZ-binding motif (TAZ) was identified as an effector protein for MSC differentiation. However, the detailed underl...
متن کاملExtracellular matrix stiffness dictates Wnt expression through integrin pathway
It is well established that extracellular matrix (ECM) stiffness plays a significant role in regulating the phenotypes and behaviors of many cell types. However, the mechanism underlying the sensing of mechanical cues and subsequent elasticity-triggered pathways remains largely unknown. We observed that stiff ECM significantly enhanced the expression level of several members of the Wnt/β-cateni...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2009
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2008.12.112